Amphetamine is understood to inhibit monoamine oxidase, whereas the power of amphetamine and its metabolites to inhibit a variety of P450 isozymes and also other enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes point out slight inhibition of CYP2D6 by amphetamine and slight inhibition of CYP1A2, 2D6, and 3A4 by